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- April 12–23, 2021
30th International World Wide Web Conference – TheWebConf'21 Virtual Edition co-located with the 18th International Web for All Conference 2021 (W4A'21)
Location: Ljubljana, Slovenia and Virtual
- April 14–16, 2021
Association of Independent Information Professionals (AIIP) Annual Conference
- April 19–21, 2021
An Event Apart Spring Summit "Online Together" a three-day web design conference with an intense focus on digital design, UX, content, code, and more.
- April 19–20, 2021
18th International Web for All Conference 2021 (W4A'21) co-located with the 30th International World Wide Web Conference – TheWebConf'21 Virtual Edition
Location: Ljubljana, Slovenia
- April 25–27, 2021
Write the Docs Portland 2021
- June 5–9, 2021
68th Society for Technical Communication (STC) Summit
- June 7–10, 2021
The 15th International AAAI Conference on Web and Social Media (ICWSM-2021)
Location: Atlanta, Georgia or Virtual
- June 9–11, 2021
Evolution of TC 2021 — Innovations in Software Documentation
- June 14–17, 2021
2021 National Hurricane Conference (Improving Hurricane Preparedness) Disaster Communication and Planning: Topics of interest: Accessibility & Functional Needs, Amateur Radio, Evacuation Planning, Fire-Rescue/Law Enforcement, Health Care, Public Education/Media, etc.
Location: Hilton Riverside, New Orleans, Louisiana
- October 3–6 2021
2021 MadWorld @ Home Virtual Conference Technical Communication and Content Strategy Conference.
Location: Austin, Texas or Virtual
- October 8–10, 2021
Communication Central Be a Better Freelancer® conference in a continuing partnership with the National Association of Independent Writers and Editors (NAIWE) and the An American Editor blog.
Location: Moonrise Hotel, St. Louis, Missouri
- October 12–14, 2021
SIGDOC 2021 Conference: Advocacy, Accountability, and Coalitions Across Contexts
Location: Virtual with optional in-person Meetup hubs around the world.
- October 24–27, 2021
LavaCon 2021: A Virtual Content Strategy Conference
- October 27–30, 2021
American Medical Writers Association (AMWA) 2021 Medical Writing and Communication Conference Spotlight on Medical Communication: Disruption, Innovation, and Resilience.
- October 27–30, 2021
American Translators Association (ATA) Conference ATA62
Location: Minneapolis, Minnesota or Virtual
- October 27–29, 2021
Clarity2021: A design systems community conference. Evaluate your skills .inclusion, empathy, technology, creativity, and collaboration.
- October 28–30, 2021
Council for Programs in Technical and Scientific Communication (CPTSC) 2021 Annual Conference
Location: Denton, Texas